Causes of Comedo Naevus

Causes of Comedo Naevus
Acne naevus

Overview

Causes of Comedo Naevus

Clinical Features

Diagnosis

Treatment

Complications

Outcome

Comedo naevus arises from somatic mutations during embryonic development, resulting in a mosaic disorder. Mutations in genes like FGFR2 and NEK9 play a role, affecting follicular differentiation. Germline mosaicism may also contribute, with earlier errors leading to increased risk.

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