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Comedo Naevus: Causes

Causes of Comedo Naevus
Acne naevus

Overview

Causes of Comedo Naevus

Clinical Features

Diagnosis

Treatment

Complications

Outcome

Comedo naevus arises from somatic mutations during embryonic development, resulting in a mosaic disorder. Mutations in genes like FGFR2 and NEK9 play a role, affecting follicular differentiation. Germline mosaicism may also contribute, with earlier errors leading to increased risk.

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